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APC Anti-Mouse IL-17A Antibody

This is a APC Anti-Mouse IL-17A Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-38A in vivo.

Synonyms

Interleukin-17A, Il17a, Ctla8

Gene ID

16171

Swiss Prot

Q62386

Reactivity

Mouse

Clonality

Monoclonal

Conjugation

APC

Type

Flow Cytometry Antibody

Applications

ICFC

Assay Type

Antibody

Concentration

0.2 mg/mL

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Host or Source

Mouse

Isotype

Mouse IgG1, κ

Available Sizes

Curated Selection

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