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AF647 Anti-Human CD16 Antibody

This is a AF647 Anti-Human CD16 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Synonyms

FcγRIII, Fc gamma receptor, Fc gamma receptor 3

Gene ID

941

Swiss Prot

P08637, O75015

Reactivity

Human

Clonality

Monoclonal

Conjugation

AF647

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Host or Source

Mouse

Isotype

Mouse IgG1, κ

Available Sizes

Curated Selection

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