APC Anti-Mouse CD200 Antibody
This is a APC Anti-Mouse CD200 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
CD200 (OX-2 antigen) is a type-1 membrane glycoprotein containing two extracellular Ig-like domains. CD200 a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells, B cells, and brain tissue (neurons) ; but not on NK cells, granulocytes, monocytes, or macrophages. CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues. CD200 is the ligand for CD200 receptor (CD200R) . The CD200 Receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in inhibition and/or downregulation of myeloid cell activity. Blocking of CD200/CD200R interactions decreases myeloid cell inhibitory thresholds which results in enhanced immune activation.
Synonyms
OX-2 membrane glycoprotein, OX-2, MRC
Gene ID
4345
Swiss Prot
O54901
Reactivity
Mouse
Clonality
Monoclonal
Conjugation
APC
Type
Flow Cytometry Antibody
Applications
FC
Assay Type
Antibody
Concentration
0.2 mg/mL
Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Host or Source
Rat
Isotype
Rat IgG2a, κ
Available Sizes
Curated Selection
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