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AFViolet 450 Anti-Human CD20 Antibody

This is a AFViolet 450 Anti-Human CD20 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn) . It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

Synonyms

Bp35, Leukocyte surface antigen Leu-16, MS4A1, B-lymphocyte surface antigen B1

Gene ID

931

Swiss Prot

P11836

Reactivity

Human

Clonality

Monoclonal

Conjugation

AFViolet 450

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Host or Source

Mouse

Isotype

Mouse IgG2b, κ

Available Sizes

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