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AFViolet 450 Anti-Human CD45RA Antibody

This is a AFViolet 450 Anti-Human CD45RA Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

Synonyms

Receptor-type tyrosine-protein phosphatase C, Ptprc, L-CA, Ly-5, T200, CD45

Gene ID

5788

Swiss Prot

P08575

Reactivity

Human

Clonality

Monoclonal

Conjugation

AFViolet 450

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Host or Source

Mouse

Isotype

Mouse IgG2b, κ

Available Sizes

Curated Selection

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