PE/AF594 Anti-Mouse CD80 Antibody
This is a PE/AF594 Anti-Mouse CD80 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Synonyms
T-lymphocyte activation antigen CD80, Cd80, Activation B7-1 antigen, B7
Gene ID
12519
Swiss Prot
Q00609
Reactivity
Mouse
Clonality
Monoclonal
Conjugation
PE/AF594
Type
Flow Cytometry Antibody
Applications
FC
Assay Type
Antibody
Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Host or Source
Armenian Hamster
Isotype
Armenian Hamster IgG
Available Sizes
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