Purified Anti-Mouse CD11c Antibody[N418]
Product Specifications
Background
CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18) . It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.
Abbreviation
CD11c
Gene ID
16411
UniProt
Q9QXH4
Host
Armenian Hamster
Reactivity
Mouse
Immunogen
Recombinant Mouse CD11c protein
Target
Leukocyte adhesion receptor p150+; CD11 antigen-like family member C; CD11c; Integrin alpha-X; Leukocyte adhesion receptor p150+95; Itgax; p150-95; CR4; integrin &alpha-X-X
Clonality
Monoclonal
Clone
N418
Conjugation
Unconjugated
Applications
FCM
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Armenian Hamster IgG
Available Sizes
Documents
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