COMP Polyclonal Antibody
This is a COMP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED) .
Synonyms
COMP, EDM1, EPD1, MED, PSACH, THBS5, TSP5
Gene ID
1311
Swiss Prot
P49747
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human COMP (NP_000086.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IF 1:10-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
77 kDa/82 kDa
Observed Molecular Weight
110 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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