RBM15 Polyclonal Antibody
This is a RBM15 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family, which have repressor function in several signaling pathway, and may bind to RNA through interaction with spliceosome components. It was first described as a 5′ translocation partner of the MAL gene in t (1,22) (p13; q13) infant acute megakaryocytic leukemia, and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation, which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation, block the cell cycle, and induce apoptosis in CML cells.
Synonyms
RBM15, OTT, OTT1, SPEN
Gene ID
64783
Swiss Prot
Q96T37
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human RBM15 (NP_001188474.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
99 kDa/104 kDa/106 kDa/107 kDa
Observed Molecular Weight
120 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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