Histone H3 Polyclonal Antibody
This is a Histone H3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Synonyms
H3.4, H3/g, H3FT, H3t, HIST3H3, Histone H3, HIST1H3A
Gene ID
8290
Swiss Prot
Q16695
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human HIST3H3 (NP_003484.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
15 kDa
Observed Molecular Weight
17 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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