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PKLR Polyclonal Antibody

This is a PKLR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA) . Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

PKLR, PK1, PKL, PKR, PKRL, RPK

Gene ID

5313

Swiss Prot

P30613

Reactivity

Human

Immunogen

Recombinant fusion protein of human PKLR (NP_000289.1) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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