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CMKLR1 Polyclonal Antibody

This is a CMKLR1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2) .

Synonyms

CMKLR1, CHEMERINR, ChemR23, DEZ, RVER1

Gene ID

1240

Swiss Prot

Q99788

Reactivity

Mouse, Rat

Immunogen

A synthetic peptide of human CMKLR1 (NP_001135815.1) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

42 kDa

Observed Molecular Weight

55 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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