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(KO Validated) SEC61B Polyclonal Antibody

This is a (KO Validated) SEC61B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.

Synonyms

SEC61B

Gene ID

10952

Swiss Prot

P60468

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human SEC61B (NP_006799.1) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000 IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

9 kDa

Observed Molecular Weight

12 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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