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IPO4 Polyclonal Antibody

This is a IPO4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Importin-4is aproteinthat in humans is encoded by theIPO4gene. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.

Synonyms

IPO4, Imp4

Gene ID

79711

Swiss Prot

Q8TEX9

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human IPO4 (NP_078934.3) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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