LRP1 Polyclonal Antibody
This is a LRP1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712) . This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients.
Synonyms
LRP1, A2MR, APOER, APR, CD91, IGFBP3R, KPA, LRP, LRP1A, TGFBR5
Gene ID
4035
Swiss Prot
Q07954
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human LRP1 (NP_002323.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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SET (2PP2A, HLA DR Associated Protein II, HLA-DR-Associated Protein II, I 2PP2A, I-2PP2A, I2PP2A, IGAAD, Inhibitor of granzyme A Activated DNase, Inhibitor of granzyme A-Activated DNase, Inhibitor of GzmA-Activated DNase, Inhibitor-2 of Protein Phosphatase-2A, IPP2A2, PHAPII, Phosphatase 2A Inhibitor I2PP2A, Protein Phosphatase Type 2A Inhibitor, Protein SET, Set, SET Nuclear Oncogene, SET Translocation, SET Translocation (Myeloid Leukemia-Associated), SET_HUMAN, TAF I, TAF IBETA, TAF-I, TAFI, Template Activating Factor I, Template-Activating Factor I, Template-Activating Factor-I, chromatin remodelling Factor, ) discontinued
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