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MKL1 Polyclonal Antibody

This is a MKL1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.

Synonyms

MKL1, BSAC, MAL, MRTF-A

Gene ID

57591

Swiss Prot

Q969V6

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human MKL1 (NP_065882.1) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000 IF 1:50-1:100

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

98 kDa

Observed Molecular Weight

150 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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