Kaolin

Kaolin is a family of kaolinitic clays, which is found in the earth's crust. Kaolin alleviates the toxicity of graphene oxide for mammalian cells. Kaolin can be utilized in industrial, cosmetic and medical fields, excipient[1][2][3][4][5].

Product Specifications

CAS Number

[1332-58-7]

UNSPSC

12352300

Hazard Statement

H302, H315, H319, H332, H335, H372

Target

Biochemical Assay Reagents; Interleukin Related; Reactive Oxygen Species (ROS) ; TNF Receptor

Type

Reference compound

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/kaolin.html

Solubility

10 mM in DMSO

Smiles

[Kaolin]

Molecular Formula

Al2Si2O5 (OH) 4

Molecular Weight

258.16

Precautions

H302, H315, H319, H332, H335, H372

References & Citations

[1]Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.|[2]Zhang Z H, et al. Geopolymer from kaolin in China: An overview[J]. Applied Clay Science, 2016, 119: 31-41.|[3]Rozhina E, et al. Kaolin alleviates the toxicity of graphene oxide for mammalian cells. Medchemcomm. 2019 Jun 10;10 (8) :1457-1464.|[4]Kato T, et al. Effect of physicochemical character differences on the genotoxic potency of kaolin. Genes Environ. 2017 May 1;39:12. |[5]Sahu AP, Shanker R, Zaidi SH. Pulmonary response to kaolin, mica and talc in mice. Exp Pathol (Jena) . 1978;16 (1-6) :276-82.