CD46 Polyclonal Antibody
This is a CD46 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
Synonyms
AHUS2, MCP, MIC10, TLX, TRA2.10, CD46
Gene ID
4179
Swiss Prot
P15529
Reactivity
Human
Immunogen
Recombinant fusion protein of human CD46 (NP_722548.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
36 kDa/39 kDa/40 kDa/41 kDa/42 kDa/43 kDa/44 kDa
Observed Molecular Weight
44 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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