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WWOX Polyclonal Antibody

This is a WWOX Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

Synonyms

WWOX, D16S432E, EIEE28, FOR, FRA16D, HHCMA56, PRO0128, SCAR12, SDR41C1, WOX1

Gene ID

51741

Swiss Prot

Q9NZC7

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human WWOX (NP_057457.1) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:1000-1:2000

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

4 kDa/21 kDa/23 kDa/26 kDa/35 kDa/41 kDa/46 kDa

Observed Molecular Weight

46 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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