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RAD51C Polyclonal Antibody

This is a RAD51C Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.

Synonyms

RAD51C, BROVCA3, FANCO, R51H3, RAD51L2

Gene ID

5889

Swiss Prot

O43502

Reactivity

Human

Immunogen

Recombinant fusion protein of human RAD51C (NP_002867.1) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

IF 1:50-1:100

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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