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SH3BP2 Polyclonal Antibody

This is a SH3BP2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

SH3BP2,3BP-2,3BP2, CRBM, CRPM, RES4-23

Gene ID

6452

Swiss Prot

P78314

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human SH3BP2 (NP_001116153.1) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

10 kDa/62 kDa/65 kDa/68 kDa

Observed Molecular Weight

75 kDa/80 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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