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HIST1H3A Polyclonal Antibody

This is a HIST1H3A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Synonyms

H3 histone family, member A, H3/A, H31, H3FA, Hist1h3a, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, histone 1, H3a, Histone cluster 1, H3a, Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3

Swiss Prot

P68431

Accession Number

NP003520

Reactivity

Human, Mouse

Immunogen

Synthetic peptide of human HIST1H3A

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

0.5 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

15 kDa

Observed Molecular Weight

Refer to figures

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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