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CENPF Polyclonal Antibody

This is a CENPF Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.

Synonyms

AH antigen, Cell cycle dependent 350K nuclear protein, CENF, CENP F, CENP F kinetochore protein, CENP-F, CENPF, CENPF kinetochore protein, CENPF, Centromere protein F 350/400ka, Centromere protein F, Centromere protein F,350/400kDa, CILD31, Hcp 1, Hcp1, Kinetochore prot

Swiss Prot

P49454

Accession Number

NP057427

Reactivity

Human

Immunogen

Synthetic peptide of human CENPF

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

1.3 mg/mL

Dilution

IHC 1:30-1:150, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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