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ZAP70 Polyclonal Antibody

This is a ZAP70 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Zeta-associated protein (ZAP) -70, a member of the Syk family of tyrosine kinases, plays an important role in T-cell receptor signaling, natural killer (NK) cell activation and early B-cell development. ZAP-70 is expressed in a subset of cases of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) with unmutated immunoglobulin heavy-chain variable region (IgVH) genes and is associated with poor clinical outcome.

Synonyms

70 kDa zeta associated protein,70 kDa zeta-associated protein, EC 2.7.10.2, FLJ17670, FLJ17679, Selective T cell defect, SRK, STD, Syk related tyrosine kinase, Syk-related tyrosine kinase, Truncated ZAP kinase, Tyrosine protein kinase ZAP70, Tyrosine-protein kinase

Swiss Prot

P43403

Accession Number

NP001070

Reactivity

Human, Mouse

Immunogen

Synthetic peptide of human ZAP70

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

0.6 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:2000-1:5000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

70 kDa

Observed Molecular Weight

Refer to figures

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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