ERLIN1 Polyclonal Antibody

The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.

Band 7 23-211 Keo4 (Interim) similar to C.elegans protein, C10orf69, chromosome 10 open reading frame 69 , Endoplasmic reticulum lipid raft-associated protein 1, ER lipid raft associated 1 , Erlin 1, Erlin-1, ERLIN1, ERLN1, KE04, KEO4, OTTHUMP00000059425, Protein KE0