PAFAH1B3 Polyclonal Antibody

This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with cognitive disability, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described.

PA1B3, PAF acetylhydrolase 29 kDa subunit, PAF AH 29 kDa subunit, PAF AH subunit gamma, PAF-AH 29 kDa subunit, PAF-AH subunit gamma, PAFAH subunit gamma, Pafah1b3, PAFAHG, Platelet activating factor acetylhydrolase IB subunit gamma, Platelet activating factor acety