ELF3 Polyclonal Antibody
This is a ELF3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity) .
Synonyms
E74 like factor 3, E74 like factor 3 ets domain transcription factor, E74 like factor 3 ets domain transcription factor epithelial specific, E74 like factor 3 ETS domain transcription factor serine box epithelial specific, E74-like factor 3, Elf3, ELF3, Epitheli
Swiss Prot
P78545
Accession Number
BC003569
Reactivity
Human
Immunogen
Fusion protein of human ELF3
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.02 mg/mL
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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