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SETMAR Polyclonal Antibody

This is a SETMAR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.

Synonyms

Histone lysine N methyltransferase, Histone lysine N methyltransferase SETMAR, Hsmar 1, Hsmar1, Mariner transposase Hsmar1, Metnase, SET domain and mariner transposase fusion, SET domain and mariner transposase fusion gene, SET domain and mariner transposase fusi

Swiss Prot

Q53H47

Accession Number

BC011635

Reactivity

Human, Mouse

Immunogen

Fusion protein of human SETMAR

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

1.8 mg/mL

Dilution

IHC 1:50-1:300, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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