ECH1 Polyclonal Antibody

This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

4) -dienoyl-CoA isomerase,5) -Delta (2, Delta (3 5) Delta (2 4) dienoyl CoA isomerase, Delta (3 5) Delta (2 4) dienoyl CoA isomerase mitochondrial, Delta (3, Delta3 5 delta2 4 dienoyl CoA isomerase, Dienoyl CoA isomerase, ECH 1, Ech1, ECH1, Enoyl Coenzyme A hydratase 1, En