ADRM1 Polyclonal Antibody
This is a ADRM1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The 26S proteasome is a key component of the ubiquitin-proteasome system, a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme, UCH37, and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts.
Synonyms
110 kDa cell membrane glycoprotein, adhesion regulating molecule 1, Adhesion-regulating molecule 1, ADRM 1, Adrm1, ADRM1, ARM 1, ARM-1, ARM1, Gp110, hRpn13, M (r) 110,000 surface antigen, Proteasomal ubiquitin receptor ADRM1, proteasome regulatory particle non ATPase 1
Swiss Prot
Q16186
Accession Number
BC017245
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human ADRM1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.54 mg/mL
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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