UBE2A Polyclonal Antibody

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants.

BHR6A, hHR6A, HR6A, mHR6A, MRXS30, MRXSN, RAD6 homolog A, RAD6A, UBC2, UBCD6, UBE2A, Ube2a ubiquitin-conjugating enzyme E2A, UBE2A, Ubiquitin carrier protein A, Ubiquitin carrier protein, Ubiquitin conjugating enzyme E2 17 kDa, Ubiquitin conjugating enzyme E2 21.5 kDa, Ub