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MICU1 Polyclonal Antibody

This is a MICU1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.

Synonyms

Allergen Hom s 4, ara CALC, atopy related autoantigen, atopy related autoantigen CALC, Atopy-related autoantigen CALC, CALC, calcium binding atopy related autoantigen 1, Calcium uptake protein 1, calcium uptake protein 1, mitochondrial, Calcium-binding atopy-relate

Swiss Prot

Q9BPX6

Accession Number

BC004190

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein of human MICU1

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

0.6 mg/mL

Dilution

IHC 1:30-1:150, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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