SPRTN Polyclonal Antibody
This is a SPRTN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS) . Alternatively spliced transcript variants have been identified.
Synonyms
C1orf124, CA124, Chromosome 1 open reading frame 124 , DDDL1880, dJ876B10.3, PRO4323, RP5-876B10.3, Spartan, SprT-like domain at the N terminus, SprT-like N-terminal domain, Zinc finger RAD18 domain-containing protein C1orf124
Swiss Prot
Q9H040
Accession Number
BC015740
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human SPRTN
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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