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SPRTN Polyclonal Antibody

This is a SPRTN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS) . Alternatively spliced transcript variants have been identified.

Synonyms

C1orf124, CA124, Chromosome 1 open reading frame 124 , DDDL1880, dJ876B10.3, PRO4323, RP5-876B10.3, Spartan, SprT-like domain at the N terminus, SprT-like N-terminal domain, Zinc finger RAD18 domain-containing protein C1orf124

Swiss Prot

Q9H040

Accession Number

BC015740

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein of human SPRTN

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

IHC 1:50-1:300, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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