UNC45B Polyclonal Antibody
This is a UNC45B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.
Synonyms
Cardiomyopathy associated 4 , CMYA4 , FLJ38610, MGC119540, MGC119541, OTTHUMP00000163855, Protein unc 45 homolog B, Protein unc-45 homolog B, SMUNC45, Striated muscle UNC45, UN45B, Unc 45 homolog B (C. elegans), Unc 45 homolog B, UNC 45B, UNC-45B, UNC45 , UNC45B
Swiss Prot
Q8IWX7
Accession Number
BC101063
Reactivity
Human, Mouse
Immunogen
Fusion protein of human UNC45B
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.9 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
104/95 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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