ZNF354A Polyclonal Antibody
This is a ZNF354A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
ZNF354A, also called EZNF, KID-1 or TCF17, belongs to the Krüppel C2H2-type zinc-finger family of proteins that contain KRAB domains and act as transcriptional regulators. Expressed primarily in the adult kidney, ZNF354A is a transcriptional repressor that plays a role in late renal development and is suppressed after renal ischemia. The N-terminus of ZNF354A contains the KRAB domain which confers transcriptional repressor activity, while the C-terminus contains multiple Cys2His2-zinc fingers. ZNF354A is located in the nucleolus and is thought to specifically influence development of the proximal tubule by shutting off dispensable or inhibitory genes. Reduced ZNF354A expression prevents proper cell differentiation and may, therefore, be implicated in renal carcinoma.
Synonyms
EZNF, HKL1, HLK1, Homo sapiens zinc finger protein 354A, KID 1, KID1, Kidney, ischemia, and developmentally regulated protein 1, Renal transcription factor Kid 1 , TCF-17, TCF17, Transcription factor 17, Z354A, Zinc finger protein 354A, Zinc finger protein eZNF, ZNF354
Swiss Prot
O60765
Accession Number
BC047105
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human ZNF354A
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.5 mg/mL
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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