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METTL7A Polyclonal Antibody

This is a METTL7A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

METTL7A (methyltransferase like 7A), also known as AAM-B, is a 244 amino acid protein that is thought to function as a methyltransferase and is encoded by a gene which maps to chromosome 12. Encoding over 1,100 genes, chromosome 12 comprises nearly 4.5% of the human genome and is associated with a number of skeletal deformaties, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to both a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and a natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Additionally, Trisomy 12p (three copies of the p arm of chromosome 12) leads to facial developmental defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism.

Synonyms

AAM B, AAMB, DKFZP586A0522, MET7A, Methyltransferase like 7A, Methyltransferase-like protein 7A, METTL 7A, METTL7A, METTL7A methlytransferase like 7A, Protein AAM-B, Protein AAMB

Swiss Prot

Q9H8H3

Accession Number

BC004492

Reactivity

Human

Immunogen

Fusion protein of human METTL7A

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

0.6 mg/mL

Dilution

IHC 1:30-1:150, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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