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ATXN7L3 Polyclonal Antibody

This is a ATXN7L3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.

Synonyms

AT7L3, Ataxin 7 like 3, Ataxin 7 like protein 3, Ataxin-7-like protein 3, atxn7l3, SAGA associated factor 11 homolog, SAGA-associated factor 11 homolog

Swiss Prot

Q14CW9

Accession Number

BC113595

Reactivity

Human, Mouse

Immunogen

Fusion protein of human ATXN7L3

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

39 kDa

Observed Molecular Weight

Refer to figures

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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