HIF1A Polyclonal Antibody

This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease.

ARNT interacting protein, ARNT-interacting protein, Basic helix loop helix PAS protein MOP1, Basic-helix-loop-helix-PAS protein MOP1, bHLHe78, Class E basic helix-loop-helix protein 78, HIF 1A, HIF 1alpha, HIF-1-alpha, HIF1 A, HIF1 Alpha, HIF1, HIF1-alpha, HIF1A, HIF1A