PTPRN Polyclonal Antibody
This is a PTPRN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
IA-2/PTPRN is a member of the protein tyrosine phosphatase (PTP) family, which contains a transmembrane region, an intracellular PTP-like domain and an extracellular N-terminus. Experiments found that IA-2/PTPRN localizes to secretory granules and is exclusively expressed in neuroendocrine cells (including pancreatic islets cell) . IA-2/PTPRNwas found to be a major autoantigen in insulin-dependent diabetes mellitus and the detection of autoantibodies against IA-2/PTPRN is commonly used as a diabetes diagnosis marker.
Synonyms
CA 512, FLJ16131, IA 2, IA 2/PTP, IA2, IA2/PTP, ICA 3, ICA 512, ICA3, ICA512, Islet cell antigen 2, Islet cell antigen 512, Islet cell autoantigen 3, Protein tyrosine phosphatase like N, Protein tyrosine phosphatase like N precursor, Protein tyrosine phosphatase recepto
Swiss Prot
Q16849
Accession Number
BC007713
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human PTPRN
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.96 mg/mL
Dilution
IHC 1:50-1:200, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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