HSD11B1 Polyclonal Antibody
This is a HSD11B1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) ) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.
Synonyms
11 beta HSD 1,11 beta HSD1,11 beta hydroxysteroid dehydrogenase 1,11 DH,11-beta hydroxysteroid dehydrogenase, type 1,11-beta-HSD1,11-beta-hydroxysteroid dehydrogenase 1,11-DH,11DH, Corticosteroid 11 beta dehydrogenase isozyme 1, Corticosteroid 11-beta-dehydr
Swiss Prot
P28845
Accession Number
BC012593
Reactivity
Human
Immunogen
Fusion protein of human HSD11B1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.2 mg/mL
Dilution
IHC 1:50-1:200, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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