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TGFBI Polyclonal Antibody

This is a TGFBI Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

TGFBI, also named as BIGH3, Kerato-epithelin and RGD-CAP, binds to type I, II, and IV collagens. TGFBI is an adhesion protein which may play an important role in cell-collagen interactions. In cartilage, it may be involved in endochondral bone formation. TGFBI is an extracellular matrix adaptor protein, it has been reported to be differentially expressed in transformed tissues. TGFBI is a predictive factor of the response to chemotherapy, and suggest the use of TGFBI-derived peptides as possible therapeutic adjuvants for the enhancement of responses to chemotherapy. Defects in TGFBI are the cause of epithelial basement membrane corneal dystrophy (EBMD) . Defects in TGFBI are the cause of corneal dystrophy Groenouw type 1 (CDGG1) . Defects in TGFBI are the cause of corneal dystrophy lattice type 1 (CDL1) . Defects in TGFBI are a cause of corneal dystrophy Thiel-Behnke type (CDTB) . Defects in TGFBI are the cause of Reis-Buecklers corneal dystrophy (CDRB) . Defects in TGFBI are the cause of lattice corneal dystrophy type 3A (CDL3A) . Defects in TGFBI are the cause of Avellino corneal dystrophy (ACD) .

Synonyms

>RGD containing collagen associated protein, AI181842, AI747162, Beta ig, Beta ig h3, Beta ig-h3, BGH3, Big h3, BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, Kerato epithelin, Kerato-epithelin, LCD1, MGC150270, RGD CAP, RGD-CAP, RGD-containing collagen-associated prote

Swiss Prot

Q15582

Accession Number

BC004972

Reactivity

Human, Mouse

Immunogen

Fusion protein of human TGFBI

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

1.32 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

75 kDa

Observed Molecular Weight

Refer to figures

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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