RCHY1 Polyclonal Antibody

The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Androgen receptor N terminal interacting protein, Androgen receptor N-terminal-interacting protein, ARNIP, CH-rich-interacting match with PLAG1, CHIMP, E3 ubiquitin-protein ligase Pirh2, hARNIP, hPirh2, p53 induced protein with a RING H2 domain, p53-induced RING-H