MCM10 Polyclonal Antibody
This is a MCM10 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Synonyms
Minichromosome Maintenance 10 Replication Initiation Factor, Minichromosome Maintenance Complex Component 10, Protein MCM10 Homolog, HsMCM10, MCM10 Minichromosome Maintenance Deficient 10 , Homolog Of Yeast MCM10, PRO2249, CNA43, DNA43
Swiss Prot
Q7L590
Accession Number
BC009108
Reactivity
Human, Mouse
Immunogen
Fusion protein of human MCM10
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.7 mg/mL
Dilution
IHC 1:35-1:200, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7041409-01 0.02 mg
Recombinant Woolly monkey hepatitis B virus Large envelope protein (S)
Ask
View Details