MAPK8 Polyclonal Antibody
This is a MAPK8 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
MAPK8 (Mitogen-activated protein kinase 8) is also named as JNK1, PRKM8, SAPK1, SAPK1C and belongs to the MAP kinase subfamily. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. MAPK8 functions to phosphorylate c-Jun at N-terminal serine regulatory sites of Ser-63 and Ser-73, mapping within the transactivation domain. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun. It has 4 isoforms produced by alternative splicing with the molecular weight of 46 kDa and 48 kDa. This protein can be phosphorylated and this antibody recognizes the 46 kDa and 55 kDa bands in western blot.
Synonyms
AI849689, c Jun N terminal kinase 1, C-JUN kinase 1, c-Jun N-terminal kinase 1, EC 2.7.11.24, JNK 1, JNK, JNK-46, JNK1A2, JNK21B1/2, MAP kinase 8, MAPK 8, mapk8, Mitogen activated protein kinase 8, Mitogen-activated protein kinase 8, MK08, p54 gamma, Prkm8, Protein kinase
Swiss Prot
P45983
Accession Number
BC130570
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human MAPK8
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.9 mg/mL
Dilution
WB 1:1000-1:5000, ELISA 1:2000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
48 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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