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CAPN3 Polyclonal Antibody

This is a CAPN3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.

Synonyms

Calcium-activated neutral proteinase 3, calpain 3, (p94), Calpain L3, Calpain large polypeptide L3 , Calpain p94, calpain p94, large [catalytic] subunit, calpain, large polypeptide L3, Calpain-3, CAN3, CANP 3, CANP3, CANPL3, CAPN3, LGMD 2A, LGMD2, LGMD2A, Lp82, Lp85, MGC10

Swiss Prot

P20807

Accession Number

BC003521

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein of human CAPN3

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Antigen affinity purification

Assay Type

Antibody

Concentration

1.4 mg/mL

Dilution

IHC 1:30-1:150, ELISA 1:5000-1:10000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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