G6PC Polyclonal Antibody
This is a G6PC Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1) . This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.
Synonyms
AW107337, G-6-Pase, G6Pase, G6Pase-alpha, g6pc, G6PC, G6PT, Glucose-6-phosphatase alpha, Glucose-6-phosphatase, GSD1, GSD1a, MGC163350, MGC93613, RP23-281C18.19
Swiss Prot
P35575
Accession Number
NP000142
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human G6PC
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
2.04 mg/mL
Dilution
IHC 1:70-1:350, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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