SNCA Polyclonal Antibody
This is a SNCA Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
Synonyms
Alpha synuclein, Alpha-synuclein, Alpha-synuclein, isoform NACP140, alphaSYN, MGC105443, MGC110988, MGC127560, MGC64356, NACP, Non A beta component of AD amyloid, Non A4 component of amyloid, Non A4 component of amyloid precursor, Non-A beta component of AD amyloid, No
Swiss Prot
P37840
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human Synuclein-α.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC-p, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:100-1:300 ELISA 1:10000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol pH 7.4.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
14 kDa
Observed Molecular Weight
15 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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