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APC Anti-Mouse CD366/Tim-3 Antibody

This is a APC Anti-Mouse CD366/Tim-3 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells) . Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

Synonyms

TIM3, TIMD3, HAVcr-2, TIMD-3

Gene ID

84868

Swiss Prot

Q8VIM0

Reactivity

Mouse

Clonality

Monoclonal

Conjugation

APC

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Host or Source

Rat

Isotype

Rat IgG2a, κ

Available Sizes

Curated Selection

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