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AF488 Anti-Mouse Ly6A/E (Sca-1) Antibody

This is a AF488 Anti-Mouse Ly6A/E (Sca-1) Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI) -linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

Synonyms

Ly6a, Ly6, Ly-6A.2/Ly-6E.1, SCA-1, TAP

Gene ID

110454

Swiss Prot

P05533

Reactivity

Mouse

Clonality

Monoclonal

Conjugation

AF488

Type

Flow Cytometry Antibody

Applications

FC

Assay Type

Antibody

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Host or Source

Rat

Isotype

Rat IgG2a, κ

Available Sizes

Curated Selection

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